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Repair at Single Targeted DNA Double-Strand Breaks in Pluripotent and Differentiated Human Cells
Differences in ex vivo cell culture conditions can drastically affect stem cell physiology. We sought to establish an assay for measuring the effects of chemical, environmental, and genetic manipulations on the precision of repair at a single DNA double-strand break (DSB) in pluripotent and somatic...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102116/ https://www.ncbi.nlm.nih.gov/pubmed/21633706 http://dx.doi.org/10.1371/journal.pone.0020514 |