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Physiology and pathophysiology of matrix metalloproteases

Matrix metalloproteases (MMPs) comprise a family of enzymes that cleave protein substrates based on a conserved mechanism involving activation of an active site-bound water molecule by a Zn(2+) ion. Although the catalytic domain of MMPs is structurally highly similar, there are many differences with...

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Detalles Bibliográficos
Autores principales: Klein, T., Bischoff, R.
Formato: Texto
Lenguaje:English
Publicado: Springer Vienna 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102199/
https://www.ncbi.nlm.nih.gov/pubmed/20640864
http://dx.doi.org/10.1007/s00726-010-0689-x