Cargando…
Evidence that Aurora B is implicated in spindle checkpoint signalling independently of error correction
Fidelity of chromosome segregation is ensured by a tension-dependent error correction system that prevents stabilization of incorrect chromosome–microtubule attachments. Unattached or incorrectly attached chromosomes also activate the spindle assembly checkpoint, thus delaying mitotic exit until all...
Autores principales: | Santaguida, Stefano, Vernieri, Claudio, Villa, Fabrizio, Ciliberto, Andrea, Musacchio, Andrea |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
European Molecular Biology Organization
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102279/ https://www.ncbi.nlm.nih.gov/pubmed/21407176 http://dx.doi.org/10.1038/emboj.2011.70 |
Ejemplares similares
-
The Aurora B Kinase in Chromosome Bi-Orientation and Spindle Checkpoint Signaling
por: Krenn, Veronica, et al.
Publicado: (2015) -
Structural analysis reveals features of the spindle checkpoint kinase Bub1–kinetochore subunit Knl1 interaction
por: Krenn, Veronica, et al.
Publicado: (2012) -
Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine
por: Santaguida, Stefano, et al.
Publicado: (2010) -
Crystal Structure of Human
Aurora B in Complex with
INCENP and VX-680
por: Elkins, Jonathan M., et al.
Publicado: (2012) -
Spindle assembly checkpoint: the third decade
por: Musacchio, Andrea
Publicado: (2011)