Cargando…

Identification of a Functional Type IA Topoisomerase, LdTopIIIβ, from Kinetoplastid Parasite Leishmania donovani

DNA topoisomerases of kinetoplastids represent a family of DNA processing enzymes that essentially solve the topological problems not only in nuclear DNA but also in kinetoplast DNA. We have, for the first time, identified a Leishmania donovani homologue of bacterial and eukaryotic IA type of topois...

Descripción completa

Detalles Bibliográficos
Autores principales:	Banerjee, Bijoylaxmi, Sen, Nilkantha, Majumder, Hemanta K.
Formato:	Texto
Lenguaje:	English
Publicado:	SAGE-Hindawi Access to Research 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102327/ https://www.ncbi.nlm.nih.gov/pubmed/21637326 http://dx.doi.org/10.4061/2011/230542

Ejemplares similares

Retraction of ‘Functional dissection of the C‐terminal domain of type II DNA topoisomerase from the kinetoplastid hemoflagellate Leishmania donovani’
por: Sengupta, Tanushri, et al.
Publicado: (2021)

‘LeishMan’ topoisomerase I: an ideal chimera for unraveling the role of the small subunit of unusual bi-subunit topoisomerase I from Leishmania donovani
por: Ganguly, Agneyo, et al.
Publicado: (2006)

Differential induction of Leishmania donovani bi-subunit topoisomerase I–DNA cleavage complex by selected flavones and camptothecin: activity of flavones against camptothecin-resistant topoisomerase I
por: Das, Benu Brata, et al.
Publicado: (2006)

Corrigendum: Identification of Leishmania donovani Topoisomerase 1 inhibitors via intuitive scaffold hopping and bioisosteric modification of known Top 1 inhibitors
por: Mamidala, Rajinikanth, et al.
Publicado: (2016)

ATP independent type IB topoisomerase of Leishmania donovani is stimulated by ATP: an insight into the functional mechanism
por: Sengupta, Souvik, et al.
Publicado: (2011)

Characterization of the DNA-binding domain and identification of the active site residue in the ‘Gyr A’ half of Leishmania donovani topoisomerase II
por: Sengupta, Tanushri, et al.
Publicado: (2005)

Development of Derivatives of 3, 3′-Diindolylmethane as Potent Leishmania donovani Bi-Subunit Topoisomerase IB Poisons
por: Roy, Amit, et al.
Publicado: (2011)

Target Identification and Intervention Strategies against Kinetoplastid Protozoan Parasites
por: Majumder, Hemanta K., et al.
Publicado: (2011)

The lignan niranthin poisons Leishmania donovani topoisomerase IB and favours a Th1 immune response in mice
por: Chowdhury, Sayan, et al.
Publicado: (2012)

Editorial Expression of Concern on article ‘Functional dissection of the C-terminal domain of type II DNA topoisomerase from the kinetoplastid hemoflagellate Leishmania donovani’
Publicado: (2021)

Isobenzofuranone derivative JVPH3, an inhibitor of L. donovani topoisomerase II, disrupts mitochondrial architecture in trypanosomatid parasites
por: Chowdhury, Somenath Roy, et al.
Publicado: (2018)

Identification of Leishmania donovani Topoisomerase 1 inhibitors via intuitive scaffold hopping and bioisosteric modification of known Top 1 inhibitors
por: Mamidala, Rajinikanth, et al.
Publicado: (2016)

Disruption of the Lipid-Transporting LdMT-LdRos3 Complex in Leishmania donovani Affects Membrane Lipid Asymmetry but Not Host Cell Invasion
por: Weingärtner, Adrien, et al.
Publicado: (2010)

Cryptolepine-Induced Cell Death of Leishmania donovani Promastigotes Is Augmented by Inhibition of Autophagy
por: Sengupta, Souvik, et al.
Publicado: (2011)

The Leishmania donovani histidine acid ecto-phosphatase LdMAcP: insight into its structure and function
por: Papadaki, Amalia, et al.
Publicado: (2015)

Fitness of Leishmania donovani Parasites Resistant to Drug Combinations
por: García-Hernández, Raquel, et al.
Publicado: (2015)

Candidates for Balancing Selection in Leishmania donovani Complex Parasites
por: Grace, Cooper Alastair, et al.
Publicado: (2021)

Mapping the Antigenicity of the Parasites in Leishmania donovani Infection by Proteome Serology
por: Forgber, Michael, et al.
Publicado: (2006)

Application of rapid in vitro co-culture system of macrophages and T-cell subsets to assess the immunogenicity of dogs vaccinated with live attenuated Leishmania donovani centrin deleted parasites (LdCen(−/−))
por: Viana, Kelvinson Fernandes, et al.
Publicado: (2016)

Deletion Study of DNA Topoisomerase IB from Leishmania donovani: Searching for a Minimal Functional Heterodimer
por: Díaz González, Rosario, et al.
Publicado: (2007)

Mechanism of Type IA Topoisomerases
por: Dasgupta, Tumpa, et al.
Publicado: (2020)

Antimonial Resistance in Leishmania donovani Is Associated with Increased In Vivo Parasite Burden
por: Vanaerschot, Manu, et al.
Publicado: (2011)

Leishmania donovani Argininosuccinate Synthase Is an Active Enzyme Associated with Parasite Pathogenesis
por: Lakhal-Naouar, Ines, et al.
Publicado: (2012)

LEISHMANIA DONOVANI IN THE PERIPHERAL BLOOD
por: Young, Charles W., et al.
Publicado: (1923)

Role of cAMP Signaling in the Survival and Infectivity of the Protozoan Parasite, Leishmania donovani
por: Biswas, Arunima, et al.
Publicado: (2011)

Leishmania donovani-Induced Increase in Macrophage Bcl-2 Favors Parasite Survival
por: Pandey, Rajeev Kumar, et al.
Publicado: (2016)

Immunization with Live Attenuated Leishmania donovani Centrin(−/−) Parasites Is Efficacious in Asymptomatic Infection
por: Ismail, Nevien, et al.
Publicado: (2017)

Unveiling Cerebral Leishmaniasis: parasites and brain inflammation in Leishmania donovani infected mice
por: Melo, Guilherme D., et al.
Publicado: (2017)

Hemophagocytosis induced by Leishmania donovani infection is beneficial to parasite survival within macrophages
por: Morimoto, Ayako, et al.
Publicado: (2019)

Editorial:New Insights into the Genomes of Kinetoplastid Parasites
por: De Pablos, Luis Miguel
Publicado: (2018)

Leishmania donovani parasite requires Atg8 protein for infectivity and survival under stress
por: Giri, Sagnik, et al.
Publicado: (2019)

Evolutionary comparison of prenylation pathway in kinetoplastid Leishmania and its sister Leptomonas
por: Chauhan, Indira Singh, et al.
Publicado: (2015)

Proteomic analysis of the secretome of Leishmania donovani
por: Silverman, J Maxwell, et al.
Publicado: (2008)

Surface antigens of Leishmania donovani promastigotes
Publicado: (1983)

Vaccine Development Against Leishmania donovani
por: Das, Amrita, et al.
Publicado: (2012)

Leishmania donovani bodies in bone marrow
por: Ali, Natasha, et al.
Publicado: (2014)

Direct Observation of Topoisomerase IA Gate Dynamics
por: Mills, Maria, et al.
Publicado: (2018)

Synthesis and in vitro Screening of 29, 30-Dibromo-28-oxoallobetulin against Parasitic Protozoans, Leishmania donovani and Leishmania Major
por: Ghosh, P., et al.
Publicado: (2015)

Natural Compounds as Anticancer Agents Targeting DNA Topoisomerases
por: Jain, Chetan Kumar, et al.
Publicado: (2017)

Non-Vesicular Lipid Transport Machinery in Leishmania donovani: Functional Implications in Host-Parasite Interaction
por: Das, Koushik, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_f9h1sbbqr911rsq16gb5663sdt