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IFN Regulatory Factors 4 and 8 Expression in the NOD Mouse

Dendritic cells (DCs) contribute to islet inflammation and its progression to diabetes in NOD mouse model and human. DCs play a crucial role in the presentation of autoantigen and activation of diabetogenic T cells, and IRF4 and IRF8 are crucial genes involved in the development of DCs. We have ther...

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Detalles Bibliográficos
Autores principales:	Besin, Gilles, Gaudreau, Simon, Dumont-Blanchette, Émilie, Ménard, Michael, Guindi, Chantal, Dupuis, Gilles, Amrani, Abdelaziz
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102445/ https://www.ncbi.nlm.nih.gov/pubmed/21647406 http://dx.doi.org/10.1155/2011/374859

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