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Discovering functional modules by identifying recurrent and mutually exclusive mutational patterns in tumors
BACKGROUND: Assays of multiple tumor samples frequently reveal recurrent genomic aberrations, including point mutations and copy-number alterations, that affect individual genes. Analyses that extend beyond single genes are often restricted to examining pathways, interactions and functional modules...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102606/ https://www.ncbi.nlm.nih.gov/pubmed/21489305 http://dx.doi.org/10.1186/1755-8794-4-34 |