p21(WAF1/CIP1) Upregulation through the Stress Granule-Associated Protein CUGBP1 Confers Resistance to Bortezomib-Mediated Apoptosis

BACKGROUND: p21(WAF1/CIP1) is a well known cyclin-dependent kinase inhibitor induced by various stress stimuli. Depending on the stress applied, p21 upregulation can either promote apoptosis or prevent against apoptotic injury. The stress-mediated induction of p21 involves not only its transcription...

Descripción completa

Detalles Bibliográficos
Autores principales: Gareau, Cristina, Fournier, Marie-Josée, Filion, Christine, Coudert, Laetitia, Martel, David, Labelle, Yves, Mazroui, Rachid
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102688/
https://www.ncbi.nlm.nih.gov/pubmed/21637851
http://dx.doi.org/10.1371/journal.pone.0020254

Ejemplares similares

Ejemplares similares