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A Linear Model for Transcription Factor Binding Affinity Prediction in Protein Binding Microarrays
Protein binding microarrays (PBM) are a high throughput technology used to characterize protein-DNA binding. The arrays measure a protein's affinity toward thousands of double-stranded DNA sequences at once, producing a comprehensive binding specificity catalog. We present a linear model for pr...
Autores principales: | Annala, Matti, Laurila, Kirsti, Lähdesmäki, Harri, Nykter, Matti |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102690/ https://www.ncbi.nlm.nih.gov/pubmed/21637853 http://dx.doi.org/10.1371/journal.pone.0020059 |
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