Microsatellite Instability in Pediatric High Grade Glioma Is Associated with Genomic Profile and Differential Target Gene Inactivation

High grade gliomas (HGG) are one of the leading causes of cancer-related deaths in children, and there is increasing evidence that pediatric HGG may harbor distinct molecular characteristics compared to adult tumors. We have sought to clarify the role of microsatellite instability (MSI) in pediatric...

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Detalles Bibliográficos
Autores principales: Viana-Pereira, Marta, Lee, Alicia, Popov, Sergey, Bax, Dorine A., Al-Sarraj, Safa, Bridges, Leslie R., Stávale, João N., Hargrave, Darren, Jones, Chris, Reis, Rui M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102740/
https://www.ncbi.nlm.nih.gov/pubmed/21637783
http://dx.doi.org/10.1371/journal.pone.0020588

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