Association of Genetic Variants in Complement Factor H and Factor H-Related Genes with Systemic Lupus Erythematosus Susceptibility

Systemic lupus erythematosus (SLE), a complex polygenic autoimmune disease, is associated with increased complement activation. Variants of genes encoding complement regulator factor H (CFH) and five CFH-related proteins (CFHR1-CFHR5) within the chromosome 1q32 locus linked to SLE, have been associa...

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Autores principales: Zhao, Jian, Wu, Hui, Khosravi, Melanie, Cui, Huijuan, Qian, Xiaoxia, Kelly, Jennifer A., Kaufman, Kenneth M., Langefeld, Carl D., Williams, Adrienne H., Comeau, Mary E., Ziegler, Julie T., Marion, Miranda C., Adler, Adam, Glenn, Stuart B., Alarcón-Riquelme, Marta E., Pons-Estel, Bernardo A., Harley, John B., Bae, Sang-Cheol, Bang, So-Young, Cho, Soo-Kyung, Jacob, Chaim O., Vyse, Timothy J., Niewold, Timothy B., Gaffney, Patrick M., Moser, Kathy L., Kimberly, Robert P., Edberg, Jeffrey C., Brown, Elizabeth E., Alarcon, Graciela S., Petri, Michelle A., Ramsey-Goldman, Rosalind, Vilá, Luis M., Reveille, John D., James, Judith A., Gilkeson, Gary S., Kamen, Diane L., Freedman, Barry I., Anaya, Juan-Manuel, Merrill, Joan T., Criswell, Lindsey A., Scofield, R. Hal, Stevens, Anne M., Guthridge, Joel M., Chang, Deh-Ming, Song, Yeong Wook, Park, Ji Ah, Lee, Eun Young, Boackle, Susan A., Grossman, Jennifer M., Hahn, Bevra H., Goodship, Timothy H. J., Cantor, Rita M., Yu, Chack-Yung, Shen, Nan, Tsao, Betty P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102741/
https://www.ncbi.nlm.nih.gov/pubmed/21637784
http://dx.doi.org/10.1371/journal.pgen.1002079

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