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Identification, Replication, and Functional Fine-Mapping of Expression Quantitative Trait Loci in Primary Human Liver Tissue

The discovery of expression quantitative trait loci (“eQTLs”) can help to unravel genetic contributions to complex traits. We identified genetic determinants of human liver gene expression variation using two independent collections of primary tissue profiled with Agilent (n = 206) and Illumina (n =...

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Detalles Bibliográficos
Autores principales: Innocenti, Federico, Cooper, Gregory M., Stanaway, Ian B., Gamazon, Eric R., Smith, Joshua D., Mirkov, Snezana, Ramirez, Jacqueline, Liu, Wanqing, Lin, Yvonne S., Moloney, Cliona, Aldred, Shelly Force, Trinklein, Nathan D., Schuetz, Erin, Nickerson, Deborah A., Thummel, Ken E., Rieder, Mark J., Rettie, Allan E., Ratain, Mark J., Cox, Nancy J., Brown, Christopher D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102751/
https://www.ncbi.nlm.nih.gov/pubmed/21637794
http://dx.doi.org/10.1371/journal.pgen.1002078