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Identification, Replication, and Functional Fine-Mapping of Expression Quantitative Trait Loci in Primary Human Liver Tissue
The discovery of expression quantitative trait loci (“eQTLs”) can help to unravel genetic contributions to complex traits. We identified genetic determinants of human liver gene expression variation using two independent collections of primary tissue profiled with Agilent (n = 206) and Illumina (n =...
Autores principales: | Innocenti, Federico, Cooper, Gregory M., Stanaway, Ian B., Gamazon, Eric R., Smith, Joshua D., Mirkov, Snezana, Ramirez, Jacqueline, Liu, Wanqing, Lin, Yvonne S., Moloney, Cliona, Aldred, Shelly Force, Trinklein, Nathan D., Schuetz, Erin, Nickerson, Deborah A., Thummel, Ken E., Rieder, Mark J., Rettie, Allan E., Ratain, Mark J., Cox, Nancy J., Brown, Christopher D. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102751/ https://www.ncbi.nlm.nih.gov/pubmed/21637794 http://dx.doi.org/10.1371/journal.pgen.1002078 |
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