An Acidic Loop and Cognate Phosphorylation Sites Define a Molecular Switch That Modulates Ubiquitin Charging Activity in Cdc34-Like Enzymes

E2 ubiquitin-conjugating enzymes are crucial mediators of protein ubiquitination, which strongly influence the ultimate fate of the target substrates. Recently, it has been shown that the activity of several enzymes of the ubiquitination pathway is finely tuned by phosphorylation, an ubiquitous mech...

Descripción completa

Detalles Bibliográficos
Autores principales: Papaleo, Elena, Ranzani, Valeria, Tripodi, Farida, Vitriolo, Alessandro, Cirulli, Claudia, Fantucci, Piercarlo, Alberghina, Lilia, Vanoni, Marco, De Gioia, Luca, Coccetti, Paola
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102755/
https://www.ncbi.nlm.nih.gov/pubmed/21637798
http://dx.doi.org/10.1371/journal.pcbi.1002056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102755/
https://www.ncbi.nlm.nih.gov/pubmed/21637798
http://dx.doi.org/10.1371/journal.pcbi.1002056

Ejemplares similares