Cargando…

Current evidence of antifungal prophylaxis and therapy in pediatric patients

Invasive fungal infections (IFI) are an important complication in pediatric haematological and oncological patients who undergo intensive chemotherapy for leukemia, solid tumour at advanced stage or relapsed, and hematopoietic stem cell transplantation. The incidence of IFI is lower than bacterial i...

Descripción completa

Detalles Bibliográficos
Autores principales: Giacchino, Mareva, Milano, Giuseppe Maria, Carraro, Francesca, Bezzio, Stefania, Pegoraro, Anna, Aversa, Franco, Cesaro, Simone
Formato: Texto
Lenguaje:English
Publicado: PAGEPress Publications 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103132/
https://www.ncbi.nlm.nih.gov/pubmed/21647279
http://dx.doi.org/10.4081/pr.2011.e6
_version_ 1782204486323798016
author Giacchino, Mareva
Milano, Giuseppe Maria
Carraro, Francesca
Bezzio, Stefania
Pegoraro, Anna
Aversa, Franco
Cesaro, Simone
author_facet Giacchino, Mareva
Milano, Giuseppe Maria
Carraro, Francesca
Bezzio, Stefania
Pegoraro, Anna
Aversa, Franco
Cesaro, Simone
author_sort Giacchino, Mareva
collection PubMed
description Invasive fungal infections (IFI) are an important complication in pediatric haematological and oncological patients who undergo intensive chemotherapy for leukemia, solid tumour at advanced stage or relapsed, and hematopoietic stem cell transplantation. The incidence of IFI is lower than bacterial infection but mortality rate remains high. This review is designed to help paediatric oncologists in choosing the appropriate anti-fungal strategy and agents for prophylaxis, empirical, pre-emptive and specific therapy on the basis of published evidence.
format Text
id pubmed-3103132
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher PAGEPress Publications
record_format MEDLINE/PubMed
spelling pubmed-31031322011-06-06 Current evidence of antifungal prophylaxis and therapy in pediatric patients Giacchino, Mareva Milano, Giuseppe Maria Carraro, Francesca Bezzio, Stefania Pegoraro, Anna Aversa, Franco Cesaro, Simone Pediatr Rep Article Invasive fungal infections (IFI) are an important complication in pediatric haematological and oncological patients who undergo intensive chemotherapy for leukemia, solid tumour at advanced stage or relapsed, and hematopoietic stem cell transplantation. The incidence of IFI is lower than bacterial infection but mortality rate remains high. This review is designed to help paediatric oncologists in choosing the appropriate anti-fungal strategy and agents for prophylaxis, empirical, pre-emptive and specific therapy on the basis of published evidence. PAGEPress Publications 2011-02-24 /pmc/articles/PMC3103132/ /pubmed/21647279 http://dx.doi.org/10.4081/pr.2011.e6 Text en ©Copyright M. Giacchino et al., 2011 This work is licensed under a Creative Commons Attribution 3.0 License (by-nc 3.0). Licensee PAGEPress, Italy
spellingShingle Article
Giacchino, Mareva
Milano, Giuseppe Maria
Carraro, Francesca
Bezzio, Stefania
Pegoraro, Anna
Aversa, Franco
Cesaro, Simone
Current evidence of antifungal prophylaxis and therapy in pediatric patients
title Current evidence of antifungal prophylaxis and therapy in pediatric patients
title_full Current evidence of antifungal prophylaxis and therapy in pediatric patients
title_fullStr Current evidence of antifungal prophylaxis and therapy in pediatric patients
title_full_unstemmed Current evidence of antifungal prophylaxis and therapy in pediatric patients
title_short Current evidence of antifungal prophylaxis and therapy in pediatric patients
title_sort current evidence of antifungal prophylaxis and therapy in pediatric patients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103132/
https://www.ncbi.nlm.nih.gov/pubmed/21647279
http://dx.doi.org/10.4081/pr.2011.e6
work_keys_str_mv AT giacchinomareva currentevidenceofantifungalprophylaxisandtherapyinpediatricpatients
AT milanogiuseppemaria currentevidenceofantifungalprophylaxisandtherapyinpediatricpatients
AT carrarofrancesca currentevidenceofantifungalprophylaxisandtherapyinpediatricpatients
AT bezziostefania currentevidenceofantifungalprophylaxisandtherapyinpediatricpatients
AT pegoraroanna currentevidenceofantifungalprophylaxisandtherapyinpediatricpatients
AT aversafranco currentevidenceofantifungalprophylaxisandtherapyinpediatricpatients
AT cesarosimone currentevidenceofantifungalprophylaxisandtherapyinpediatricpatients