5-Azacytidine in Chronic Myelomonocytic Leukemia: Case Report and Review of Literature.

Hypomethylating drugs are useful in the management of Myelodysplastic syndromes, but there are only few reports on chronic myelomonocycitic (CMML) leukemia patients. We describe our experience in 3 CMML patients treated with azacitidine. Two patients obtained partial response after 4 treatment cycle...

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Detalles Bibliográficos
Autores principales: Greco, M., Criscuolo, M., Fianchi, L., Fabiani, E., Pagano, L., Voso, MT.
Formato: Texto
Lenguaje:English
Publicado: Università Cattolica del Sacro Cuore 2011
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103239/
https://www.ncbi.nlm.nih.gov/pubmed/21625315
http://dx.doi.org/10.4084/MJHID.2011.011
Descripción
Sumario:Hypomethylating drugs are useful in the management of Myelodysplastic syndromes, but there are only few reports on chronic myelomonocycitic (CMML) leukemia patients. We describe our experience in 3 CMML patients treated with azacitidine. Two patients obtained partial response after 4 treatment cycles with only minor toxicity and are in continuous partial response, with stable peripheral blood counts, at 29 and 30 cycles from treatment start.

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