5-Azacytidine in Chronic Myelomonocytic Leukemia: Case Report and Review of Literature.

Hypomethylating drugs are useful in the management of Myelodysplastic syndromes, but there are only few reports on chronic myelomonocycitic (CMML) leukemia patients. We describe our experience in 3 CMML patients treated with azacitidine. Two patients obtained partial response after 4 treatment cycle...

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Detalles Bibliográficos
Autores principales: Greco, M., Criscuolo, M., Fianchi, L., Fabiani, E., Pagano, L., Voso, MT.
Formato: Texto
Lenguaje:English
Publicado: Università Cattolica del Sacro Cuore 2011
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103239/
https://www.ncbi.nlm.nih.gov/pubmed/21625315
http://dx.doi.org/10.4084/MJHID.2011.011
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author Greco, M.
Criscuolo, M.
Fianchi, L.
Fabiani, E.
Pagano, L.
Voso, MT.
author_facet Greco, M.
Criscuolo, M.
Fianchi, L.
Fabiani, E.
Pagano, L.
Voso, MT.
author_sort Greco, M.
collection PubMed
description Hypomethylating drugs are useful in the management of Myelodysplastic syndromes, but there are only few reports on chronic myelomonocycitic (CMML) leukemia patients. We describe our experience in 3 CMML patients treated with azacitidine. Two patients obtained partial response after 4 treatment cycles with only minor toxicity and are in continuous partial response, with stable peripheral blood counts, at 29 and 30 cycles from treatment start.
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spelling pubmed-31032392011-05-27 5-Azacytidine in Chronic Myelomonocytic Leukemia: Case Report and Review of Literature. Greco, M. Criscuolo, M. Fianchi, L. Fabiani, E. Pagano, L. Voso, MT. Mediterr J Hematol Infect Dis Case Reports Hypomethylating drugs are useful in the management of Myelodysplastic syndromes, but there are only few reports on chronic myelomonocycitic (CMML) leukemia patients. We describe our experience in 3 CMML patients treated with azacitidine. Two patients obtained partial response after 4 treatment cycles with only minor toxicity and are in continuous partial response, with stable peripheral blood counts, at 29 and 30 cycles from treatment start. Università Cattolica del Sacro Cuore 2011-03-15 /pmc/articles/PMC3103239/ /pubmed/21625315 http://dx.doi.org/10.4084/MJHID.2011.011 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Greco, M.
Criscuolo, M.
Fianchi, L.
Fabiani, E.
Pagano, L.
Voso, MT.
5-Azacytidine in Chronic Myelomonocytic Leukemia: Case Report and Review of Literature.
title 5-Azacytidine in Chronic Myelomonocytic Leukemia: Case Report and Review of Literature.
title_full 5-Azacytidine in Chronic Myelomonocytic Leukemia: Case Report and Review of Literature.
title_fullStr 5-Azacytidine in Chronic Myelomonocytic Leukemia: Case Report and Review of Literature.
title_full_unstemmed 5-Azacytidine in Chronic Myelomonocytic Leukemia: Case Report and Review of Literature.
title_short 5-Azacytidine in Chronic Myelomonocytic Leukemia: Case Report and Review of Literature.
title_sort 5-azacytidine in chronic myelomonocytic leukemia: case report and review of literature.
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103239/
https://www.ncbi.nlm.nih.gov/pubmed/21625315
http://dx.doi.org/10.4084/MJHID.2011.011
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