Tyrosine phosphorylation of Munc18c on residue 521 abrogates binding to Syntaxin 4

BACKGROUND: Insulin stimulates exocytosis of GLUT4 from an intracellular store to the cell surface of fat and muscle cells. Fusion of GLUT4-containing vesicles with the plasma membrane requires the SNARE proteins Syntaxin 4, VAMP2 and the regulatory Sec1/Munc18 protein, Munc18c. Syntaxin 4 and Munc1...

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Detalles Bibliográficos
Autores principales: Aran, Veronica, Bryant, Nia J, Gould, Gwyn W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103433/
https://www.ncbi.nlm.nih.gov/pubmed/21548926
http://dx.doi.org/10.1186/1471-2091-12-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103433/
https://www.ncbi.nlm.nih.gov/pubmed/21548926
http://dx.doi.org/10.1186/1471-2091-12-19

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