Cargando…
Tyrosine phosphorylation of Munc18c on residue 521 abrogates binding to Syntaxin 4
BACKGROUND: Insulin stimulates exocytosis of GLUT4 from an intracellular store to the cell surface of fat and muscle cells. Fusion of GLUT4-containing vesicles with the plasma membrane requires the SNARE proteins Syntaxin 4, VAMP2 and the regulatory Sec1/Munc18 protein, Munc18c. Syntaxin 4 and Munc1...
| Autores principales: | , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103433/ https://www.ncbi.nlm.nih.gov/pubmed/21548926 http://dx.doi.org/10.1186/1471-2091-12-19 |