Cargando…
Alpha-fetoprotein-producing primary lung carcinoma: A case report
Alpha-fetoprotein (AFP)-producing lung adenocarcinoma is a rare type of lung cancer, with its characteristics not yet fully clarified. We recently encountered a case of this type of lung cancer. The patient was a 69-year-old man who consulted an internist with the chief complaint of epigastric pain....
Autores principales: | , , , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103442/ https://www.ncbi.nlm.nih.gov/pubmed/21554678 http://dx.doi.org/10.1186/1477-7819-9-47 |
_version_ | 1782204515781443584 |
---|---|
author | Kitada, Masahiro Ozawa, Keisuke Sato, Kazuhiro Matsuda, Yoshinari Hayashi, Satoshi Tokusashi, Yoshihiko Miyokawa, Naoyuki Sasajima, Tadahiro |
author_facet | Kitada, Masahiro Ozawa, Keisuke Sato, Kazuhiro Matsuda, Yoshinari Hayashi, Satoshi Tokusashi, Yoshihiko Miyokawa, Naoyuki Sasajima, Tadahiro |
author_sort | Kitada, Masahiro |
collection | PubMed |
description | Alpha-fetoprotein (AFP)-producing lung adenocarcinoma is a rare type of lung cancer, with its characteristics not yet fully clarified. We recently encountered a case of this type of lung cancer. The patient was a 69-year-old man who consulted an internist with the chief complaint of epigastric pain. Chest X-ray and CT revealed a lobulated mass measuring 70 mm in diameter in the right lower lung field and a metastasis in the right hilar lymph nodes. Of the tumor markers, the serum AFP was elevated (4620 ng/ml), and the serum carcinoembryonic antigen and carbohydrate antigen 19-9 were also slightly elevated. Transbronchial lung biopsy revealed the diagnosis of lung cancer. Under thoracoscopic assistance, right lower lobectomy + mediastinal lymph node dissection was carried out. Immunostaining showed the tumor cells to be AFP-positive. The tumor was thus diagnosed as an AFP-producing lung adenocarcinoma. The patient followed an uneventful clinical course after the surgery, with serum AFP decreasing to the normal range by about 2 weeks after the surgery. As of this writing, no sign of tumor recurrence has been noted. This case is presented here with a review of the literature. |
format | Text |
id | pubmed-3103442 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-31034422011-05-28 Alpha-fetoprotein-producing primary lung carcinoma: A case report Kitada, Masahiro Ozawa, Keisuke Sato, Kazuhiro Matsuda, Yoshinari Hayashi, Satoshi Tokusashi, Yoshihiko Miyokawa, Naoyuki Sasajima, Tadahiro World J Surg Oncol Case Report Alpha-fetoprotein (AFP)-producing lung adenocarcinoma is a rare type of lung cancer, with its characteristics not yet fully clarified. We recently encountered a case of this type of lung cancer. The patient was a 69-year-old man who consulted an internist with the chief complaint of epigastric pain. Chest X-ray and CT revealed a lobulated mass measuring 70 mm in diameter in the right lower lung field and a metastasis in the right hilar lymph nodes. Of the tumor markers, the serum AFP was elevated (4620 ng/ml), and the serum carcinoembryonic antigen and carbohydrate antigen 19-9 were also slightly elevated. Transbronchial lung biopsy revealed the diagnosis of lung cancer. Under thoracoscopic assistance, right lower lobectomy + mediastinal lymph node dissection was carried out. Immunostaining showed the tumor cells to be AFP-positive. The tumor was thus diagnosed as an AFP-producing lung adenocarcinoma. The patient followed an uneventful clinical course after the surgery, with serum AFP decreasing to the normal range by about 2 weeks after the surgery. As of this writing, no sign of tumor recurrence has been noted. This case is presented here with a review of the literature. BioMed Central 2011-05-09 /pmc/articles/PMC3103442/ /pubmed/21554678 http://dx.doi.org/10.1186/1477-7819-9-47 Text en Copyright ©2011 Kitada et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Kitada, Masahiro Ozawa, Keisuke Sato, Kazuhiro Matsuda, Yoshinari Hayashi, Satoshi Tokusashi, Yoshihiko Miyokawa, Naoyuki Sasajima, Tadahiro Alpha-fetoprotein-producing primary lung carcinoma: A case report |
title | Alpha-fetoprotein-producing primary lung carcinoma: A case report |
title_full | Alpha-fetoprotein-producing primary lung carcinoma: A case report |
title_fullStr | Alpha-fetoprotein-producing primary lung carcinoma: A case report |
title_full_unstemmed | Alpha-fetoprotein-producing primary lung carcinoma: A case report |
title_short | Alpha-fetoprotein-producing primary lung carcinoma: A case report |
title_sort | alpha-fetoprotein-producing primary lung carcinoma: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103442/ https://www.ncbi.nlm.nih.gov/pubmed/21554678 http://dx.doi.org/10.1186/1477-7819-9-47 |
work_keys_str_mv | AT kitadamasahiro alphafetoproteinproducingprimarylungcarcinomaacasereport AT ozawakeisuke alphafetoproteinproducingprimarylungcarcinomaacasereport AT satokazuhiro alphafetoproteinproducingprimarylungcarcinomaacasereport AT matsudayoshinari alphafetoproteinproducingprimarylungcarcinomaacasereport AT hayashisatoshi alphafetoproteinproducingprimarylungcarcinomaacasereport AT tokusashiyoshihiko alphafetoproteinproducingprimarylungcarcinomaacasereport AT miyokawanaoyuki alphafetoproteinproducingprimarylungcarcinomaacasereport AT sasajimatadahiro alphafetoproteinproducingprimarylungcarcinomaacasereport |