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HIV-1-Infected and Immune-Activated Macrophages Induce Astrocytic Differentiation of Human Cortical Neural Progenitor Cells via the STAT3 Pathway
Diminished adult neurogenesis is considered a potential mechanism in the pathogenesis of HIV-1-associated dementia (HAD). In HAD, HIV-1-infected and immune-activated brain mononuclear phagocytes (MP; perivascular macrophages and microglia) drive central nervous system (CNS) inflammation and may alte...
Autores principales: | Peng, Hui, Sun, Lijun, Jia, Beibei, Lan, Xiqian, Zhu, Bing, Wu, Yumei, Zheng, Jialin |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103496/ https://www.ncbi.nlm.nih.gov/pubmed/21637744 http://dx.doi.org/10.1371/journal.pone.0019439 |
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