Lack of the Long Pentraxin PTX3 Promotes Autoimmune Lung Disease but not Glomerulonephritis in Murine Systemic Lupus Erythematosus

The long pentraxin PTX3 has multiple roles in innate immunity. For example, PTX3 regulates C1q binding to pathogens and dead cells and regulates their uptake by phagocytes. It also inhibits P-selectin-mediated recruitment of leukocytes. Both of these mechanisms are known to be involved in autoimmuni...

Descripción completa

Detalles Bibliográficos
Autores principales: Lech, Maciej, Römmele, Christoph, Kulkarni, Onkar P., Susanti, Heni Eka, Migliorini, Adriana, Garlanda, Cecilia, Mantovani, Alberto, Anders, Hans-Joachim
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103530/
https://www.ncbi.nlm.nih.gov/pubmed/21637713
http://dx.doi.org/10.1371/journal.pone.0020118

Ejemplares similares

Ejemplares similares