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Markov Models of Amino Acid Substitution to Study Proteins with Intrinsically Disordered Regions
BACKGROUND: Intrinsically disordered proteins (IDPs) or proteins with disordered regions (IDRs) do not have a well-defined tertiary structure, but perform a multitude of functions, often relying on their native disorder to achieve the binding flexibility through changing to alternative conformations...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
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Public Library of Science
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103576/ https://www.ncbi.nlm.nih.gov/pubmed/21647374 http://dx.doi.org/10.1371/journal.pone.0020488 |