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Canakinumab reduces the risk of acute gouty arthritis flares during initiation of allopurinol treatment: results of a double-blind, randomised study

OBJECTIVE: This study assessed the efficacy and safety of canakinumab, a fully human anti-interleukin 1β monoclonal antibody, for prophylaxis against acute gouty arthritis flares in patients initiating urate-lowering treatment. METHODS: In this double-blind, double-dummy, dose-ranging study, 432 pat...

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Detalles Bibliográficos
Autores principales:	Schlesinger, Naomi, Mysler, Eduardo, Lin, Hsiao-Yi, De Meulemeester, Marc, Rovensky, Jozef, Arulmani, Udayasankar, Balfour, Alison, Krammer, Gerhard, Sallstig, Peter, So, Alexander
Formato:	Texto
Lenguaje:	English
Publicado:	BMJ Group 2011
Materias:	Clinical and Epidemiological Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103669/ https://www.ncbi.nlm.nih.gov/pubmed/21540198 http://dx.doi.org/10.1136/ard.2010.144063

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