Pharmacoperone Identification for Therapeutic Rescue of Misfolded Mutant Proteins

G protein-coupled receptors (GPCRs), which includes the gonadotropin-releasing hormone (GnRH) receptor (GnRHR), comprises the largest family of validated drug targets – more than half of all approved drugs derive their benefits by selective targeting of GPCRs. Most drugs in this class are either ago...

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Detalles Bibliográficos
Autores principales: Conn, P. Michael, Janovick, Jo Ann
Formato: Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103854/
https://www.ncbi.nlm.nih.gov/pubmed/21633718
http://dx.doi.org/10.3389/fendo.2011.00006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103854/
https://www.ncbi.nlm.nih.gov/pubmed/21633718
http://dx.doi.org/10.3389/fendo.2011.00006

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