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Pharmacoperone Identification for Therapeutic Rescue of Misfolded Mutant Proteins
G protein-coupled receptors (GPCRs), which includes the gonadotropin-releasing hormone (GnRH) receptor (GnRHR), comprises the largest family of validated drug targets – more than half of all approved drugs derive their benefits by selective targeting of GPCRs. Most drugs in this class are either ago...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Research Foundation
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103854/ https://www.ncbi.nlm.nih.gov/pubmed/21633718 http://dx.doi.org/10.3389/fendo.2011.00006 |