In vitro antimicrobial activity of methanolic leaf extract of Psidium guajava L.

AIM: This study was designed to examine the chemical composition and in vitro antimicrobial potential of methanolic extract of Psidium guajava Linn (Myrtaceae). MATERIALS AND METHODS: The inhibitory effect of methanolic extract of P. guajava was tested against three bacterial and two fungal strains...

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Detalles Bibliográficos
Autores principales: Dhiman, Anju, Nanda, Arun, Ahmad, Sayeed, Narasimhan, B.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications Pvt Ltd 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103916/
https://www.ncbi.nlm.nih.gov/pubmed/21687350
http://dx.doi.org/10.4103/0975-7406.80776
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author Dhiman, Anju
Nanda, Arun
Ahmad, Sayeed
Narasimhan, B.
author_facet Dhiman, Anju
Nanda, Arun
Ahmad, Sayeed
Narasimhan, B.
author_sort Dhiman, Anju
collection PubMed
description AIM: This study was designed to examine the chemical composition and in vitro antimicrobial potential of methanolic extract of Psidium guajava Linn (Myrtaceae). MATERIALS AND METHODS: The inhibitory effect of methanolic extract of P. guajava was tested against three bacterial and two fungal strains by using the paper disc diffusion method. RESULTS: The methanolic extract exhibited antibacterial activity against E. coli with minimum inhibitory concentration, 0.78 μg/ml, minimum bactericidal concentration of 50 μg/ml, and appreciable antifungal activity with minimum inhibitory concentration of 12.5 μg/ml. Preliminary phytochemical analysis of methanolic extract revealed the presence of antimicrobial compounds such as flavonoids, steroids, and tannins, which may contribute for the antimicrobial action of P. guajava. CONCLUSION: The extract was found to be bacteriostatic and fungistatic in action.
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spelling pubmed-31039162011-06-16 In vitro antimicrobial activity of methanolic leaf extract of Psidium guajava L. Dhiman, Anju Nanda, Arun Ahmad, Sayeed Narasimhan, B. J Pharm Bioallied Sci Original Article AIM: This study was designed to examine the chemical composition and in vitro antimicrobial potential of methanolic extract of Psidium guajava Linn (Myrtaceae). MATERIALS AND METHODS: The inhibitory effect of methanolic extract of P. guajava was tested against three bacterial and two fungal strains by using the paper disc diffusion method. RESULTS: The methanolic extract exhibited antibacterial activity against E. coli with minimum inhibitory concentration, 0.78 μg/ml, minimum bactericidal concentration of 50 μg/ml, and appreciable antifungal activity with minimum inhibitory concentration of 12.5 μg/ml. Preliminary phytochemical analysis of methanolic extract revealed the presence of antimicrobial compounds such as flavonoids, steroids, and tannins, which may contribute for the antimicrobial action of P. guajava. CONCLUSION: The extract was found to be bacteriostatic and fungistatic in action. Medknow Publications Pvt Ltd 2011 /pmc/articles/PMC3103916/ /pubmed/21687350 http://dx.doi.org/10.4103/0975-7406.80776 Text en © Journal of Pharmacy and Bioallied Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Dhiman, Anju
Nanda, Arun
Ahmad, Sayeed
Narasimhan, B.
In vitro antimicrobial activity of methanolic leaf extract of Psidium guajava L.
title In vitro antimicrobial activity of methanolic leaf extract of Psidium guajava L.
title_full In vitro antimicrobial activity of methanolic leaf extract of Psidium guajava L.
title_fullStr In vitro antimicrobial activity of methanolic leaf extract of Psidium guajava L.
title_full_unstemmed In vitro antimicrobial activity of methanolic leaf extract of Psidium guajava L.
title_short In vitro antimicrobial activity of methanolic leaf extract of Psidium guajava L.
title_sort in vitro antimicrobial activity of methanolic leaf extract of psidium guajava l.
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103916/
https://www.ncbi.nlm.nih.gov/pubmed/21687350
http://dx.doi.org/10.4103/0975-7406.80776
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