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Increased expression of the chemokines CXCL1 and MIP-1α by resident brain cells precedes neutrophil infiltration in the brain following prolonged soman-induced status epilepticus in rats
BACKGROUND: Exposure to the nerve agent soman (GD) causes neuronal cell death and impaired behavioral function dependent on the induction of status epilepticus (SE). Little is known about the maturation of this pathological process, though neuroinflammation and infiltration of neutrophils are promin...
Autores principales: | Johnson, Erik A, Dao, Thuy L, Guignet, Michelle A, Geddes, Claire E, Koemeter-Cox, Andrew I, Kan, Robert K |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3104356/ https://www.ncbi.nlm.nih.gov/pubmed/21535896 http://dx.doi.org/10.1186/1742-2094-8-41 |
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