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Toll-Like Receptor 4 Signaling is Involved in IgA-Stimulated Mesangial Cell Activation

PURPOSE: Deposition of polymeric IgA1 in the kidney mesangium is the hallmark of IgA nephropathy, but the molecular mechanisms of IgA-mediated mesangial responses and inflammatory injuries remain poorly understood. We hypothesize that Toll-like receptor 4 (TLR4) is involved in IgA-induced mesangial...

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Detalles Bibliográficos
Autores principales:	Lim, Beom Jin, Lee, Dahye, Hong, Soon Won, Jeong, Hyeon Joo
Formato:	Texto
Lenguaje:	English
Publicado:	Yonsei University College of Medicine 2011
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3104456/ https://www.ncbi.nlm.nih.gov/pubmed/21623603 http://dx.doi.org/10.3349/ymj.2011.52.4.610

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