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Rapid cell-surface prion protein conversion revealed using a novel cell system

Prion diseases are fatal neurodegenerative disorders with unique transmissible properties. The infectious and pathological agent is thought to be a misfolded conformer of the prion protein. Little is known about the initial events in prion infection because the infecting prion source has been immuno...

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Detalles Bibliográficos
Autores principales: Goold, R., Rabbanian, S., Sutton, L., Andre, R., Arora, P., Moonga, J., Clarke, A.R., Schiavo, G., Jat, P., Collinge, J., Tabrizi, S.J.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3104518/
https://www.ncbi.nlm.nih.gov/pubmed/21505437
http://dx.doi.org/10.1038/ncomms1282