Respiratory distress and perinatal lethality in Nedd4-2-deficient mice

The epithelial sodium channel (ENaC) is essential for sodium homoeostasis in many epithelia. ENaC activity is required for lung fluid clearance in newborn animals and for maintenance of blood volume and blood pressure in adults. In vitro studies show that the ubiquitin ligase Nedd4-2 ubiquitinates E...

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Detalles Bibliográficos
Autores principales: Boase, Natasha A., Rychkov, Grigori Y., Townley, Scott L., Dinudom, Anuwat, Candi, Eleanora, Voss, Anne K., Tsoutsman, Tatiana, Semsarian, Chris, Melino, Gerry, Koentgen, Frank, Cook, David I., Kumar, Sharad
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3104547/
https://www.ncbi.nlm.nih.gov/pubmed/21505443
http://dx.doi.org/10.1038/ncomms1284

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