Cutaneous Granular Cell Tumor of the Breast: A Clinical Diagnostic Pitfall

We report the clinical-morphological study of a granular cell tumor in dermal/hypodermal junction and subcutaneous fat left breast of an 83-year-old woman with a family history of breast carcinoma. Mammography study showed a spiculated lesion in the lower inner quadrant with suspicion of malignancy....

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Autores principales: Aneiros-Fernandez, Jose, Arias-Santiago, Salvador, Husein-ElAhmed, Husein, OValle, Francisco, Siendones, Maria Ines Aroca, Aneiros-Cachaza, Jose
Formato: Texto
Lenguaje:English
Publicado: Elmer Press 2010
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3104657/
https://www.ncbi.nlm.nih.gov/pubmed/21629537
http://dx.doi.org/10.4021/jocmr403w
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author Aneiros-Fernandez, Jose
Arias-Santiago, Salvador
Husein-ElAhmed, Husein
OValle, Francisco
Siendones, Maria Ines Aroca
Aneiros-Cachaza, Jose
author_facet Aneiros-Fernandez, Jose
Arias-Santiago, Salvador
Husein-ElAhmed, Husein
OValle, Francisco
Siendones, Maria Ines Aroca
Aneiros-Cachaza, Jose
author_sort Aneiros-Fernandez, Jose
collection PubMed
description We report the clinical-morphological study of a granular cell tumor in dermal/hypodermal junction and subcutaneous fat left breast of an 83-year-old woman with a family history of breast carcinoma. Mammography study showed a spiculated lesion in the lower inner quadrant with suspicion of malignancy. The results of fine needle puncture-aspiration were inconclusive. Subsequent tumorectomy revealed a poorly-defined indurated lesion of 1.1 × 0.7 cm. The histopathology study showed a proliferation of cells with ample and granular cytoplasm that were positive for S100, CD 68 and inhibin and negative for hormonal receptors. We present a benign lesion that clinically reproduces a breast carcinoma. KEYWORDS: Granular cell tumor; Breast; Differential diagnosis; Cutaneous
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spelling pubmed-31046572011-05-31 Cutaneous Granular Cell Tumor of the Breast: A Clinical Diagnostic Pitfall Aneiros-Fernandez, Jose Arias-Santiago, Salvador Husein-ElAhmed, Husein OValle, Francisco Siendones, Maria Ines Aroca Aneiros-Cachaza, Jose J Clin Med Res Case Report We report the clinical-morphological study of a granular cell tumor in dermal/hypodermal junction and subcutaneous fat left breast of an 83-year-old woman with a family history of breast carcinoma. Mammography study showed a spiculated lesion in the lower inner quadrant with suspicion of malignancy. The results of fine needle puncture-aspiration were inconclusive. Subsequent tumorectomy revealed a poorly-defined indurated lesion of 1.1 × 0.7 cm. The histopathology study showed a proliferation of cells with ample and granular cytoplasm that were positive for S100, CD 68 and inhibin and negative for hormonal receptors. We present a benign lesion that clinically reproduces a breast carcinoma. KEYWORDS: Granular cell tumor; Breast; Differential diagnosis; Cutaneous Elmer Press 2010-08 2010-08-18 /pmc/articles/PMC3104657/ /pubmed/21629537 http://dx.doi.org/10.4021/jocmr403w Text en Copyright © 2010, Aneiros-Fernandez et al. http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Aneiros-Fernandez, Jose
Arias-Santiago, Salvador
Husein-ElAhmed, Husein
OValle, Francisco
Siendones, Maria Ines Aroca
Aneiros-Cachaza, Jose
Cutaneous Granular Cell Tumor of the Breast: A Clinical Diagnostic Pitfall
title Cutaneous Granular Cell Tumor of the Breast: A Clinical Diagnostic Pitfall
title_full Cutaneous Granular Cell Tumor of the Breast: A Clinical Diagnostic Pitfall
title_fullStr Cutaneous Granular Cell Tumor of the Breast: A Clinical Diagnostic Pitfall
title_full_unstemmed Cutaneous Granular Cell Tumor of the Breast: A Clinical Diagnostic Pitfall
title_short Cutaneous Granular Cell Tumor of the Breast: A Clinical Diagnostic Pitfall
title_sort cutaneous granular cell tumor of the breast: a clinical diagnostic pitfall
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3104657/
https://www.ncbi.nlm.nih.gov/pubmed/21629537
http://dx.doi.org/10.4021/jocmr403w
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