Cargando…
Chronic Refractory Uveitis in a Patient with Childhood-Onset Cyclic Neutropenia
We report a rare case of chronic refractory uveitis in a patient with childhood-onset cyclic neutropenia (CN). A 19-year-old woman, who had a history of CN beginning at age 2, presented with bilateral chronic nongranulomatous uveitis, complicated cataract, retinal vasculitis, cystoids macular edema,...
Autores principales: | , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3104861/ https://www.ncbi.nlm.nih.gov/pubmed/21677883 http://dx.doi.org/10.1159/000328748 |
_version_ | 1782204647127121920 |
---|---|
author | Chen, Li-Li Toyoguchi, Mitsuko Shimakawa, Machiko Hori, Sadao |
author_facet | Chen, Li-Li Toyoguchi, Mitsuko Shimakawa, Machiko Hori, Sadao |
author_sort | Chen, Li-Li |
collection | PubMed |
description | We report a rare case of chronic refractory uveitis in a patient with childhood-onset cyclic neutropenia (CN). A 19-year-old woman, who had a history of CN beginning at age 2, presented with bilateral chronic nongranulomatous uveitis, complicated cataract, retinal vasculitis, cystoids macular edema, and vitreous hemorrhage. She had recurrent episodes of oral ulcers, tonsillitis, genital ulcers, and folliculitis during neutropenic nadir. After the resumption of granulocyte colony-stimulating factor therapy for her CN, vitreous hemorrhage in both eyes followed. Her eyes were treated with topical corticosteroids, retinal photocoagulation, and cataract surgery. Blood and bone marrow test results confirmed the diagnosis of CN. She also fulfilled the diagnostic criteria of Behçet's disease, though clinical features of her uveitis were dissimilar to those found in that disease. |
format | Text |
id | pubmed-3104861 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-31048612011-06-14 Chronic Refractory Uveitis in a Patient with Childhood-Onset Cyclic Neutropenia Chen, Li-Li Toyoguchi, Mitsuko Shimakawa, Machiko Hori, Sadao Case Rep Ophthalmol Published: May 2011 We report a rare case of chronic refractory uveitis in a patient with childhood-onset cyclic neutropenia (CN). A 19-year-old woman, who had a history of CN beginning at age 2, presented with bilateral chronic nongranulomatous uveitis, complicated cataract, retinal vasculitis, cystoids macular edema, and vitreous hemorrhage. She had recurrent episodes of oral ulcers, tonsillitis, genital ulcers, and folliculitis during neutropenic nadir. After the resumption of granulocyte colony-stimulating factor therapy for her CN, vitreous hemorrhage in both eyes followed. Her eyes were treated with topical corticosteroids, retinal photocoagulation, and cataract surgery. Blood and bone marrow test results confirmed the diagnosis of CN. She also fulfilled the diagnostic criteria of Behçet's disease, though clinical features of her uveitis were dissimilar to those found in that disease. S. Karger AG 2011-05-13 /pmc/articles/PMC3104861/ /pubmed/21677883 http://dx.doi.org/10.1159/000328748 Text en Copyright © 2011 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions. |
spellingShingle | Published: May 2011 Chen, Li-Li Toyoguchi, Mitsuko Shimakawa, Machiko Hori, Sadao Chronic Refractory Uveitis in a Patient with Childhood-Onset Cyclic Neutropenia |
title | Chronic Refractory Uveitis in a Patient with Childhood-Onset Cyclic Neutropenia |
title_full | Chronic Refractory Uveitis in a Patient with Childhood-Onset Cyclic Neutropenia |
title_fullStr | Chronic Refractory Uveitis in a Patient with Childhood-Onset Cyclic Neutropenia |
title_full_unstemmed | Chronic Refractory Uveitis in a Patient with Childhood-Onset Cyclic Neutropenia |
title_short | Chronic Refractory Uveitis in a Patient with Childhood-Onset Cyclic Neutropenia |
title_sort | chronic refractory uveitis in a patient with childhood-onset cyclic neutropenia |
topic | Published: May 2011 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3104861/ https://www.ncbi.nlm.nih.gov/pubmed/21677883 http://dx.doi.org/10.1159/000328748 |
work_keys_str_mv | AT chenlili chronicrefractoryuveitisinapatientwithchildhoodonsetcyclicneutropenia AT toyoguchimitsuko chronicrefractoryuveitisinapatientwithchildhoodonsetcyclicneutropenia AT shimakawamachiko chronicrefractoryuveitisinapatientwithchildhoodonsetcyclicneutropenia AT horisadao chronicrefractoryuveitisinapatientwithchildhoodonsetcyclicneutropenia |