Frosted Branch Angiitis Diagnosed as Neuro-Behçet: A Diagnostic and Etiologic Dilemma

PURPOSE: To report a case of frosted branch angiitis (FBA) secondary to neuro-Behçet. METHODS: Description, diagnosis, angiogram imaging and follow-up of a 28-year-old female with FBA. RESULTS: ‘Frosted branch angiitis’ is a clinical term applied to three conditions: infiltration of vessels by malignant cells, and sheathing of vessels either secondary to an active disorder or subsequently to a previous inflammatory disease. Our patient's history of two optic neuropathies and the lack of demyelinating signs in neuroimaging made us consider FBA in the context of neuro-Behçet. CONCLUSION: Recognition of the category of FBA from the clinical signs is essential to establish the correct diagnosis and prescribe the appropriate treatment.