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VX Hydrolysis by Human Serum Paraoxonase 1: A Comparison of Experimental and Computational Results

Human Serum paraoxonase 1 (HuPON1) is an enzyme that has been shown to hydrolyze a variety of chemicals including the nerve agent VX. While wildtype HuPON1 does not exhibit sufficient activity against VX to be used as an in vivo countermeasure, it has been suggested that increasing HuPON1's org...

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Detalles Bibliográficos
Autores principales:	Peterson, Matthew W., Fairchild, Steven Z., Otto, Tamara C., Mohtashemi, Mojdeh, Cerasoli, Douglas M., Chang, Wenling E.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105050/ https://www.ncbi.nlm.nih.gov/pubmed/21655255 http://dx.doi.org/10.1371/journal.pone.0020335

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