Nicotinic Acid Receptor Abnormalities in Human Skin Cancer: Implications for a Role in Epidermal Differentiation

BACKGROUND: Chronic UV skin exposure leads to epidermal differentiation defects in humans that can be largely restored by pharmacological doses of nicotinic acid. Nicotinic acid has been identified as a ligand for the human G-protein-coupled receptors GPR109A and GPR109B that signal through G(i)-med...

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Detalles Bibliográficos
Autores principales: Bermudez, Yira, Benavente, Claudia A., Meyer, Ralph G., Coyle, W. Russell, Jacobson, Myron K., Jacobson, Elaine L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105069/
https://www.ncbi.nlm.nih.gov/pubmed/21655214
http://dx.doi.org/10.1371/journal.pone.0020487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105069/
https://www.ncbi.nlm.nih.gov/pubmed/21655214
http://dx.doi.org/10.1371/journal.pone.0020487

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