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Endogenous Synthesis of n-3 Polyunsaturated Fatty Acids in Fat-1 Mice Is Associated with Increased Mammary Gland and Liver Syndecan-1
Long chain n-3 PUFA have been shown to have chemopreventive properties against breast cancer through various mechanisms. One pathway, studied in human breast cancer cell lines, involves upregulation of the proteoglycan, syndecan-1 (SDC-1) by n-3 PUFA-enriched LDL. Using Fat-1 mice that are able to c...
Autores principales: | Sun, Haiguo, Hu, Yunping, Gu, Zhennan, Wilson, Martha D., Chen, Yong Q., Rudel, Lawrence L., Willingham, Mark C., Edwards, Iris J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105073/ https://www.ncbi.nlm.nih.gov/pubmed/21655218 http://dx.doi.org/10.1371/journal.pone.0020502 |
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