Cargando…

Identification of Novel Schizophrenia Loci by Homozygosity Mapping Using DNA Microarray Analysis

The recent development of high-resolution DNA microarrays, in which hundreds of thousands of single nucleotide polymorphisms (SNPs) are genotyped, enables the rapid identification of susceptibility genes for complex diseases. Clusters of these SNPs may show runs of homozygosity (ROHs) that can be an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kurotaki, Naohiro, Tasaki, Shinya, Mishima, Hiroyuki, Ono, Shinji, Imamura, Akira, Kikuchi, Taeko, Nishida, Nao, Tokunaga, Katsushi, Yoshiura, Koh-ichiro, Ozawa, Hiroki
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105082/ https://www.ncbi.nlm.nih.gov/pubmed/21655227 http://dx.doi.org/10.1371/journal.pone.0020589

Ejemplares similares

Deep sequencing reveals variations in somatic cell mosaic mutations between monozygotic twins with discordant psychiatric disease
por: Morimoto, Yoshiro, et al.
Publicado: (2017)

A unique missense variant in the E1A-binding protein P400 gene is implicated in schizophrenia by whole-exome sequencing and mutant mouse models
por: Morimoto, Yoshiro, et al.
Publicado: (2021)

Genetic and epigenetic analyses of panic disorder in the post-GWAS era
por: Morimoto, Yoshiro, et al.
Publicado: (2020)

Whole-exome sequencing and gene-based rare variant association tests suggest that PLA2G4E might be a risk gene for panic disorder
por: Morimoto, Yoshiro, et al.
Publicado: (2018)

Nonsense mutation in CFAP43 causes normal-pressure hydrocephalus with ciliary abnormalities
por: Morimoto, Yoshiro, et al.
Publicado: (2019)

Genetic and environmental factors of schizophrenia and autism spectrum disorder: insights from twin studies
por: Imamura, Akira, et al.
Publicado: (2020)

Genome-Wide Association Study Reveals Host Genetic Factors for Liver Diseases
por: Nishida, Nao, et al.
Publicado: (2013)

Likelihood Ratio Test for Excess Homozygosity at Marker Loci on X Chromosome
por: You, Xiao-Ping, et al.
Publicado: (2015)

Highly Parallel and Short-Acting Amplification with Locus-Specific Primers to Detect Single Nucleotide Polymorphisms by the DigiTag2 Assay
por: Nishida, Nao, et al.
Publicado: (2012)

Comparative analysis of copy number variation detection methods and database construction
por: Koike, Asako, et al.
Publicado: (2011)

Evolutionary Analysis of Classical HLA Class I and II Genes Suggests That Recent Positive Selection Acted on DPB1*04∶01 in Japanese Population
por: Kawashima, Minae, et al.
Publicado: (2012)

KinSNP software for homozygosity mapping of disease genes using SNP microarrays
por: Amir, El-Ad David, et al.
Publicado: (2010)

HomozygosityMapper—an interactive approach to homozygosity mapping
por: Seelow, Dominik, et al.
Publicado: (2009)

Genome-wide copy number variation analysis of hepatitis B infection in a Japanese population
por: Kikuchi, Masataka, et al.
Publicado: (2021)

Significance of genomic instability in breast cancer in atomic bomb survivors: analysis of microarray-comparative genomic hybridization
por: Oikawa, Masahiro, et al.
Publicado: (2011)

PT608. Analysis of glutamate-induced processing of proline-rich transmembrane protein 2 (PRRT2)
por: Hatta, Daisuke, et al.
Publicado: (2016)

Agile parallel bioinformatics workflow management using Pwrake
por: Mishima, Hiroyuki, et al.
Publicado: (2011)

Long contiguous stretches of homozygosity detected by chromosomal microarrays (CMA) in patients with neurodevelopmental disorders in the South of Brazil
por: Chaves, Tiago Fernando, et al.
Publicado: (2019)

Long contiguous stretches of homozygosity spanning shortly the imprinted loci are associated with intellectual disability, autism and/or epilepsy
por: Iourov, Ivan Y., et al.
Publicado: (2015)

HomozygosityMapper2012—bridging the gap between homozygosity mapping and deep sequencing
por: Seelow, Dominik, et al.
Publicado: (2012)

A detailed characteristics of bias associated with long runs of homozygosity identification based on medium density SNP microarrays
por: Szmatoła, Tomasz, et al.
Publicado: (2020)

A quantitatively-modeled homozygosity mapping algorithm, qHomozygosityMapping, utilizing whole genome single nucleotide polymorphism genotyping data
por: Huqun*, et al.
Publicado: (2010)

The Ruby UCSC API: accessing the UCSC genome database using Ruby
por: Mishima, Hiroyuki, et al.
Publicado: (2012)

Proto-oncogene mutations in middle ear cholesteatoma contribute to its pathogenesis
por: Satoh, Chisei, et al.
Publicado: (2023)

NELFCD and CTSZ loci are associated with jaundice-stage progression in primary biliary cholangitis in the Japanese population
por: Nishida, Nao, et al.
Publicado: (2018)

Principal contribution of HLA-DQ alleles, DQB1*06:04 and DQB1*03:01, to disease resistance against primary biliary cholangitis in a Japanese population
por: Yasunami, Michio, et al.
Publicado: (2017)

KAT6B-related disorder in a patient with a novel frameshift variant (c.3925dup)
por: Hamaguchi, Yo, et al.
Publicado: (2019)

Evaluating the performance of Affymetrix SNP Array 6.0 platform with 400 Japanese individuals
por: Nishida, Nao, et al.
Publicado: (2008)

Identification of a haplotype block in the 5q31 cytokine gene cluster associated with the susceptibility to severe malaria
por: Naka, Izumi, et al.
Publicado: (2009)

Genomic prediction based on runs of homozygosity
por: Luan, Tu, et al.
Publicado: (2014)

Runs of homozygosity and population history in cattle
por: Purfield, Deirdre C, et al.
Publicado: (2012)

Inbreeding and homozygosity in breast cancer survival
por: Thomsen, Hauke, et al.
Publicado: (2015)

Runs of homozygosity and inbreeding in thyroid cancer
por: Thomsen, Hauke, et al.
Publicado: (2016)

Homozygosity disequilibrium and its gene regulation
por: Yang, Hsin-Chou, et al.
Publicado: (2016)

A novel mutation in GLUD1 causing hyperinsulinism-hyperammonemia in a patient with high density of homozygosity on microarray: a case report
por: Odom, John, et al.
Publicado: (2016)

Excessive homozygosity identified by chromosomal microarray at a known GCDH mutation locus correlates with brain MRI abnormalities in an infant with glutaric aciduria
por: Peer‐Zada, Abdul Ali, et al.
Publicado: (2017)

Copy number variant and runs of homozygosity detection by microarrays enabled more precise molecular diagnoses in 11,020 clinical exome cases
por: Dharmadhikari, Avinash V., et al.
Publicado: (2019)

A single-nucleotide-polymorphism in the 5′-flanking region of MSX1 gene as a predictive marker candidate for platinum-based therapy of esophageal carcinoma
por: Mori, Takahiro, et al.
Publicado: (2022)

Extended homozygosity is not usually due to cytogenetic abnormality
por: Curtis, David
Publicado: (2007)

Patterns of homozygosity in insular and continental goat breeds
por: Cardoso, Taina F., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_hjjgcl8e27fj9g7o3lehqtb0pg