Genes of the Unfolded Protein Response Pathway Harbor Risk Alleles for Primary Open Angle Glaucoma

The statistical power of genome-wide association (GWA) studies to detect risk alleles for human diseases is limited by the unfavorable ratio of SNPs to study subjects. This multiple testing problem can be surmounted with very large population sizes when common alleles of large effects give rise to d...

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Detalles Bibliográficos
Autores principales: Carbone, Mary Anna, Chen, Yuhong, Hughes, Guy A., Weinreb, Robert N., Zabriskie, Norman A., Zhang, Kang, Anholt, Robert R. H.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105107/
https://www.ncbi.nlm.nih.gov/pubmed/21655191
http://dx.doi.org/10.1371/journal.pone.0020649

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