Differential use of importin-α isoforms governs cell tropism and host adaptation of influenza virus

Influenza A viruses are a threat to humans due to their ability to cross species barriers, as illustrated by the 2009 H1N1v pandemic and sporadic H5N1 transmissions. Interspecies transmission requires adaptation of the viral polymerase to importin-α, a cellular protein that mediates transport into t...

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Detalles Bibliográficos
Autores principales: Gabriel, Gülsah, Klingel, Karin, Otte, Anna, Thiele, Swantje, Hudjetz, Ben, Arman-Kalcek, Gökhan, Sauter, Martina, Shmidt, Tatiana, Rother, Franziska, Baumgarte, Sigrid, Keiner, Björn, Hartmann, Enno, Bader, Michael, Brownlee, George G., Fodor, Ervin, Klenk, Hans-Dieter
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105303/
https://www.ncbi.nlm.nih.gov/pubmed/21245837
http://dx.doi.org/10.1038/ncomms1158

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