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Leucine-rich repeat kinase LRRK1 regulates endosomal trafficking of the EGF receptor
Activation of the epidermal growth factor receptor (EGFR) not only initiates multiple signal-transduction pathways, including the MAP kinase (MAPK) pathway, but also triggers trafficking events that relocalize receptors from the cell surface to intracellular endocytic compartments. In this paper, we...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105304/ https://www.ncbi.nlm.nih.gov/pubmed/21245839 http://dx.doi.org/10.1038/ncomms1161 |