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Prostaglandin E2 and SOCS1 have a role in intestinal immune tolerance

Interleukin 10 (IL-10) and regulatory T cells (Tregs) maintain tolerance to intestinal microorganisms. However, Il10(−/−)Rag2(−/−) mice, which lack IL-10 and Tregs, remain healthy, suggesting the existence of other mechanisms of tolerance. Here, we identify suppressor of cytokine signalling 1 (SOCS1...

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Detalles Bibliográficos
Autores principales:	Chinen, Takatoshi, Komai, Kyoko, Muto, Go, Morita, Rimpei, Inoue, Naoko, Yoshida, Hideyuki, Sekiya, Takashi, Yoshida, Ryoko, Nakamura, Kazuhiko, Takayanagi, Ryoichi, Yoshimura, Akihiko
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105338/ https://www.ncbi.nlm.nih.gov/pubmed/21304519 http://dx.doi.org/10.1038/ncomms1181

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