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Probing RNA dynamics via longitudinal exchange and CPMG relaxation dispersion NMR spectroscopy using a sensitive (13)C-methyl label
The refolding kinetics of bistable RNA sequences were studied in unperturbed equilibrium via (13)C exchange NMR spectroscopy. For this purpose a straightforward labeling technique was elaborated using a 2′-(13)C-methoxy uridine modification, which was prepared by a two-step synthesis and introduced...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105391/ https://www.ncbi.nlm.nih.gov/pubmed/21252295 http://dx.doi.org/10.1093/nar/gkq1361 |