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Induced topological changes in DNA complexes: influence of DNA sequences and small molecule structures

Heterocyclic diamidines are compounds with antiparasitic properties that target the minor groove of kinetoplast DNA. The mechanism of action of these compounds is unknown, but topological changes to DNA structures are likely to be involved. In this study, we have developed a polyacrylamide gel elect...

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Detalles Bibliográficos
Autores principales:	Hunt, Rebecca A., Munde, Manoj, Kumar, Arvind, Ismail, Mohamed A., Farahat, Abdelbasset A., Arafa, Reem K., Say, Martial, Batista-Parra, Adalgisa, Tevis, Denise, Boykin, David W., Wilson, W. David
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105405/ https://www.ncbi.nlm.nih.gov/pubmed/21266485 http://dx.doi.org/10.1093/nar/gkq1362

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