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R5X4 HIV-1 coreceptor use in primary target cells: implications for coreceptor entry blocking strategies
Entry coreceptor use by HIV-1 plays a pivotal role in viral transmission, pathogenesis and disease progression. In many HIV-1 infected individuals, there is an expansion in coreceptor use from CCR5 to include CXCR4, which is associated with accelerated disease progression. While targeting HIV-1 enve...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105503/ https://www.ncbi.nlm.nih.gov/pubmed/21284902 http://dx.doi.org/10.1186/1479-5876-9-S1-S3 |