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A Topical Microbicide Gel Formulation of CCR5 Antagonist Maraviroc Prevents HIV-1 Vaginal Transmission in Humanized RAG-hu Mice

For prevention of HIV infection many currently licensed anti-HIV drugs and new ones in the pipeline show potential as topically applied microbicides. While macaque models have been the gold standard for in vivo microbicide testing, they are expensive and sufficient numbers are not available. Therefo...

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Detalles Bibliográficos
Autores principales:	Neff, C. Preston, Kurisu, Theresa, Ndolo, Thomas, Fox, Kami, Akkina, Ramesh
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105981/ https://www.ncbi.nlm.nih.gov/pubmed/21673796 http://dx.doi.org/10.1371/journal.pone.0020209

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