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Expanding the Understanding of Biases in Development of Clinical-Grade Molecular Signatures: A Case Study in Acute Respiratory Viral Infections
BACKGROUND: The promise of modern personalized medicine is to use molecular and clinical information to better diagnose, manage, and treat disease, on an individual patient basis. These functions are predominantly enabled by molecular signatures, which are computational models for predicting phenoty...
Autores principales: | Lytkin, Nikita I., McVoy, Lauren, Weitkamp, Jörn-Hendrik, Aliferis, Constantin F., Statnikov, Alexander |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105991/ https://www.ncbi.nlm.nih.gov/pubmed/21673802 http://dx.doi.org/10.1371/journal.pone.0020662 |
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