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IL-10 expression by primary tumor cells correlates with melanoma progression from radial to vertical growth phase and development of metastatic competence
Down-regulation of the immune system facilitates tumor progression at different stages of cutaneous melanoma. Sentinel nodes, the first lymph nodes on lymphatics draining directly from a primary melanoma are immune down-regulated by tumor-generated immune-suppressive cytokines including interleukin-...
Autores principales: | Itakura, Eijun, Huang, Rong-Rong, Wen, Duan-Ren, Paul, Eberhard, Wünsch, Peter H., Cochran, Alistair J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3106125/ https://www.ncbi.nlm.nih.gov/pubmed/21317876 http://dx.doi.org/10.1038/modpathol.2011.5 |
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