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Centromere fission, not telomere erosion, triggers chromosomal instability in human carcinomas
The majority of sporadic carcinomas suffer from a kind of genetic instability in which chromosome number changes occur together with segmental defects. This means that changes involving intact chromosomes accompany breakage-induced alterations. Whereas the causes of aneuploidy are described in detai...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3106440/ https://www.ncbi.nlm.nih.gov/pubmed/21478459 http://dx.doi.org/10.1093/carcin/bgr069 |