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The nature, scope and impact of genomic prediction in beef cattle in the United States

Artificial selection has proven to be effective at altering the performance of animal production systems. Nevertheless, selection based on assessment of the genetic superiority of candidates is suboptimal as a result of errors in the prediction of genetic merit. Conventional breeding programs may ex...

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Autor principal: Garrick, Dorian J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107171/
https://www.ncbi.nlm.nih.gov/pubmed/21569623
http://dx.doi.org/10.1186/1297-9686-43-17
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author Garrick, Dorian J
author_facet Garrick, Dorian J
author_sort Garrick, Dorian J
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description Artificial selection has proven to be effective at altering the performance of animal production systems. Nevertheless, selection based on assessment of the genetic superiority of candidates is suboptimal as a result of errors in the prediction of genetic merit. Conventional breeding programs may extend phenotypic measurements on selection candidates to include correlated indicator traits, or delay selection decisions well beyond puberty so that phenotypic performance can be observed on progeny or other relatives. Extending the generation interval to increase the accuracy of selection reduces annual rates of gain compared to accurate selection and use of parents of the next generation at the immediate time they reach breeding age. Genomic prediction aims at reducing prediction errors at breeding age by exploiting information on the transmission of chromosome fragments from parents to selection candidates, in conjunction with knowledge on the value of every chromosome fragment. For genomic prediction to influence beef cattle breeding programs and the rate or cost of genetic gains, training analyses must be undertaken, and genomic prediction tools made available for breeders and other industry stakeholders. This paper reviews the nature or kind of studies currently underway, the scope or extent of some of those studies, and comments on the likely predictive value of genomic information for beef cattle improvement.
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spelling pubmed-31071712011-06-03 The nature, scope and impact of genomic prediction in beef cattle in the United States Garrick, Dorian J Genet Sel Evol Review Artificial selection has proven to be effective at altering the performance of animal production systems. Nevertheless, selection based on assessment of the genetic superiority of candidates is suboptimal as a result of errors in the prediction of genetic merit. Conventional breeding programs may extend phenotypic measurements on selection candidates to include correlated indicator traits, or delay selection decisions well beyond puberty so that phenotypic performance can be observed on progeny or other relatives. Extending the generation interval to increase the accuracy of selection reduces annual rates of gain compared to accurate selection and use of parents of the next generation at the immediate time they reach breeding age. Genomic prediction aims at reducing prediction errors at breeding age by exploiting information on the transmission of chromosome fragments from parents to selection candidates, in conjunction with knowledge on the value of every chromosome fragment. For genomic prediction to influence beef cattle breeding programs and the rate or cost of genetic gains, training analyses must be undertaken, and genomic prediction tools made available for breeders and other industry stakeholders. This paper reviews the nature or kind of studies currently underway, the scope or extent of some of those studies, and comments on the likely predictive value of genomic information for beef cattle improvement. BioMed Central 2011-05-15 /pmc/articles/PMC3107171/ /pubmed/21569623 http://dx.doi.org/10.1186/1297-9686-43-17 Text en Copyright ©2011 Garrick; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Garrick, Dorian J
The nature, scope and impact of genomic prediction in beef cattle in the United States
title The nature, scope and impact of genomic prediction in beef cattle in the United States
title_full The nature, scope and impact of genomic prediction in beef cattle in the United States
title_fullStr The nature, scope and impact of genomic prediction in beef cattle in the United States
title_full_unstemmed The nature, scope and impact of genomic prediction in beef cattle in the United States
title_short The nature, scope and impact of genomic prediction in beef cattle in the United States
title_sort nature, scope and impact of genomic prediction in beef cattle in the united states
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107171/
https://www.ncbi.nlm.nih.gov/pubmed/21569623
http://dx.doi.org/10.1186/1297-9686-43-17
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