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Epistasis between Beneficial Mutations and the Phenotype-to-Fitness Map for a ssDNA Virus
Epistatic interactions between genes and individual mutations are major determinants of the evolutionary properties of genetic systems and have therefore been well documented, but few quantitative data exist on epistatic interactions between beneficial mutations, presumably because such mutations ar...
Autores principales: | Rokyta, Darin R., Joyce, Paul, Caudle, S. Brian, Miller, Craig, Beisel, Craig J., Wichman, Holly A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107187/ https://www.ncbi.nlm.nih.gov/pubmed/21655079 http://dx.doi.org/10.1371/journal.pgen.1002075 |
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